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beta oxidation
In biochemistry and metabolism, beta-oxidation is the catabolic process by which fatty acid molecules are broken down in the mitochondria to generate acetyl-CoA, which enters the citric acid cycle, and NADH and FADH2, which are co-enzymes used in the electron transport chain. It is named as such because the beta carbon of the fatty acid undergoes oxidation to a carbonyl group. Various mechanisms have evolved to handle the large variety of fatty acids.
==Overview==
Fatty acid catabolism consists of:
#Activation and membrane transport of free fatty acids by binding to coenzyme A.
#Oxidation of the beta carbon to a carbonyl group.
#Cleavage of two-carbon segments resulting in acetyl-CoA.
#Oxidation of acetyl-CoA to carbon dioxide in the citric acid cycle.
#Electron transfer from electron carriers to the electron transfer chain in oxidative phosphorylation.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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